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Liraglutide and semaglutide are GLP-1 RAs whereas tirzepatide is a combined agonist to both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

We have to assume it'd be even worse when ingested orally

Typical protocol structure: Dose: 100-200mcg based on individual response Frequency: 3-5 times per week Timing: 1-3 hours before bed (experiment to find your optimal window) Cycle length: 4-8 weeks Break period: 2-4 weeks between cycles The frequency debate generates significant discussion